IMBA® Internal Dosimetry Software

IMBALite includes the core functionality provided by the "Base Unit" of previous versions of IMBA Professional Plus, but it is now applicable to an extended and very comprehensive list of radionuclides (formerly only available through the purchase of two additional radionuclide packs).

The Base Unit is the core of all three versions of IMBA® and enables the user to perform basic internal dosimetry calculations. It implements biokinetic and dosimetric models which are recommended by the International Commission on Radiological Protection (ICRP) for the Reference Worker (ICRP 68 and US 10 CFR 835) and applies the methodology described in ICRP Publication 60. Output is both tabular and graphical and special tools enable data transfer between Windows applications.

For standard calculations, all of the default values can be selected from built-in databases at the touch of a button. For more detailed calculations, the user can enter individual parameter values. Calculations are performed 6-10 times faster than in the previous software (IMBA® Expert/Professional Series). The product has been extensively quality assured and comes with complete documentation.

The IMBALite Lite version is intended for the user who does not require all of the advanced features provided by the previous modular Add-Ons. More advanced functionality, to meet the needs of internal dose specialists and researchers is now provided through IMBAPlus and IMBAPro

The IMBA® Lite enables you to do the following:

  • Assess intakes from inhalation, ingestion, injection or transdermal wounds by using bioassay measurement data
  • Calculate bioassay quantities as a function of time - implemented quantities are: Whole Body, Lungs, Urine, Faeces, Blood, Thyroid, Liver, User Defined function
  • Calculate equivalent organ doses and effective dose from a single intake

 

The IMBA® Lite includes the following basic features. This functionality is now applicable to an extended and very comprehensive list of radionuclides which includes 75 radionuclides, previously implemented in the Base Unit, and further 665 radionuclides, previously implemented within Additional Radionuclide Packs 1 and 2 (see information sheet for a list of all radionuclides).:

  • Calculate the best estimate of the amount of intake - from a single exposure event (intake regime), based on the user-specified intake scenario
  • Analyse any of the above types of bioassay measurement - for a given indicator radionuclide
  • Specify the date and time-of-day of each bioassay measurement
  • Specify the collection period for each urine and faecal sample (as a fraction of a day)
  • Define all absorption parameter values and aerosol characteristics - or select the absorption parameters from a built-in database of International Commission on Radiological Protection (ICRP)-recommended values
  • Define bioassay retention functions - or select these from a database of ICRP-recommended values
  • Toggle between ICRP 60/68, ICRP26, or 10 CFR 835 tissue weighting factors and remainder tissue rules
  • Enter user specified particle transport rates (in the respiratory tract) - or use ICRP defaults - and perform calculations for both Reference Worker light activity and heavy activity
  • Apply built-in ICRP biokinetic models for each element - or specify user-defined models
  • Apply the built-in ICRP Publication 38 radiation database - and view complete decay chains and nuclear data on-screen
  • The ability to deal with chelated intakes by marking and excluding treatment-enhanced excretion data from the intake assessment
  • Apply the maximum likelihood fitting method - to deal with:
    • data recorded as less than the limit of detection (< LOD)
    • explicit error on each data point
    • normal or lognormal error distributions
    • up to 200 data points
  • Exclude unreliable data points from the fitting process - but not from the data record - and mark these as such in the associated graph of the data
  • Calculate the committed equivalent dose to each organ or tissue - and the effective dose - from an indicator radionuclide
  • Toggle between pCi and Bq activity units
  • Calculate bioassay quantities over specified time intervals - for design of future monitoring programs
  • Display bioassay data (with error bars and the fitted bioassay function) graphically on-screen - in multiple windows
  • Interchangeably display tables of bioassay data and predicted bioassay quantities with graphs of the same quantities
  • Use built-in, highly flexible, graphical and spreadsheet tools to facilitate setting up your own graphs and data entry
  • Import/export bioassay data between IMBA® and a Windows spreadsheet
  • Copy data to-and-from spreadsheets and other Windows applications
  • Copy data to-and-from an ASCII file
  • Create a comprehensive report file containing administrative details, all case parameter assumptions, and the calculated results
  • Save all assumptions, parameter values and results to a single, nameable data file which can be read in to any version of IMBA®, running on any compatible PC computer system
  • Save and reload all assumed parameter values and calculated results for a particular case study in a comprehensive parameter file